Patients are admitted on day of procedure, or earlier if less fit. Must be arranged in advance via ultradound sec or by discussin with radiologist who has a list. If deemed suitable for day care, can be assessed by Clinical Nurse Practitioner. If admitted to general wards to be assessed by medical staff.
 

Pre-procedure  

aspirin/clopidogrel stop 1 week in advance; other NSAIDs omitted on the day
warfarin stop AT LEAST 2 days in advance if indication permits.  Some patients will need iv heparin until day of biopsy
all medications including anti-hypertensives and anti-anginals to continue (usually patients' own supply)

pathology request form must be filled in by renal team and attached to front of notes. Do same with consent form if obtained in advance

Fluids only for 2 hours prior to procedure but no need to fast

 

Investigations and observations

Ensure no major change in condition or therapy (seek advice if there is)

Recent results for the following must be available:

FBC (Hb must be > 80 g/l, Pts > 100x1012/l)
coag screen ( PT and APTT must be within 3 seconds of control value)
Group and save
U & E in patients on dialysis, or if uraemic
if any values are outwith these ranges the Registrar and the radiologist should be informed

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Consent

May be obtained in OPD. Should be attached to front of notes, with pathology request form. Inform of small risk of bleeding, very small risk of requiring intervention (including  surgery). See patient info.

Edinburgh: Consent form should be attached to front of notes, with pathology request form

  

Post-procedure

bed rest 6hrs: first 2h lying flat

pulse and BP:

  • Half-hourly  for 2 hours
  • then hourly  for 2 hours
  • At 6h, then 6-hourly to 24h if still an in-patient
advise patient to drink plenty
pain relief: paracetamol is adequate in most instances

assess and document:

  • biopsy site
  • presence/absence of haematuria (macroscopically  only)
  • dialysis or uraemic patients: check [K] the following day
Aspirin  and warfarin can be restarted the following day if uncomplicated
Discuss reintroduction of heparin if patient at high risk of thrombosis

  

Discharge

At the agreed time if all the above satisfactory. Minimum is 6h if suitable for day-case biopsy, see below. In all cases,

patient must have passed urine
6h or final BP must have been recorded
patient must have been given a number to call if problems (renal ward or doctor)
results usually given at an outpatient appointment in the near future
returning to work and other activities: a day or two off work is usually enough. Heavy manual activities should be avoided for a few days. No other special precautions are required.

 

 

Day case biopsies

These are suitable if the following conditions can be met

 

Inclusion criteria:

Low risk
Suitable responsible person at home
Can arrange own transport for evening discharge

 

Exclusion criteria:

Anticoagulation
Creatinine >250 micromol/l
Serious comorbid disease


Diabetes mellitus does not automatically exclude day case biopsy as there is no requirement to fast.
Patients must have an appropriately early biopsy.

 

Urgent biopsies - warn renal pathologist

Out of hours procedures - contact the consultant pathologist first

  

Further information

Patient information explaining renal biopsy is available from EdRenINFO

 

Acknowledgements:   Angela Webster and Paul Allan were the main authors for this page. It was updated in July 2002 by Anne Petherick, and reviewed September 2003 and November 2006. It was last updated Thursday, November 30, 2006.

 

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