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Treatment depends on classification on histology and the clinical status of patient.
 
Acute Cellular rejection (ACR)

1. Type IA IB acute cellular rejection (no evidence of vascular or antibody-mediated rejection)

Methyl prednisolone 500mg IV daily for 3 doses
Consider ATG if steroid resistant cellular rejection
 

2. Type IIA, IIB OR  vascular rejection

MP 500mg IV daily for 3 doses with ATG  (see protocol below)

IF ATG GIVEN FOR LATE ACR, VALGANCICLOVIR AND COTRIMOXAZOLE SHOULD BE GIVEN FOR 6 -12 WEEKS (see KDIGO GUIDELINES) AND 3 MONTHS RESPECTIVELY.

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This page last modified 07.10.2013 14:53 by Emma Farrell. edren and edrep are produced by the Renal Unit at the Royal Infirmary of Edinburgh and the University of Edinburgh. CAUTIONS and Contact us.